Guidelines on the non-clinical evaluation of vaccine adjuvants and adjuvanted vaccines, Annex 2, TRS No 987

Overview

Full version of the WHO Technical Report Series N° 987

These Guidelines are intended to provide guidance to NRAs and manufacturers on the nonclinical and initial clinical evaluation of vaccine adjuvants and adjuvanted vaccines by outlining international regulatory expectations in this area. The Guidelines should be read in conjunction with existing WHO guidelines on nonclinical (1) and clinical (2) evaluation of vaccines.