Core variables For AEFI
For optimal vaccine safety monitoring and meaningful analysis of Adverse Event Following Immunization (AEFI) data, systematic and standard collection of critical parameters is essential. A limited number of variables are required to properly manage AEFI information. This includes a unique identification of the report, the primary source of information, patient characteristics, details of the event(s) and vaccine(s) of interest and the possibility of collecting additional information if needed.
Comparing AEFI reporting forms from a sample of emerging countries, a WHO working group developed a core data set that was endorsed by the Global Advisory Committee on Vaccine Safety (GACVS) in June 2012. This data set includes 22 variables with 10 identified as critical. This simple structure is expected to provide countries with a harmonized template that will simplify AEFI reporting and allow for comparisons and pooling of essential information for action.