New results from RTS,S/AS01 malaria vaccine trial
WHO notes the completion of the latest stage of the RTS,S/AS01 Phase 3 malaria vaccine trial.
As communicated previously, WHO will make evidence-based recommendations in 2015. These recommendations will be based on the full results from the Phase 3 trial that will become available in 2014, including the site-specific efficacy and booster dose data. WHO recommendations are based on the input of its independent advisors. For malaria vaccines, the Joint Technical Expert Group (JTEG) on malaria vaccines will draft candidate policy recommendations for joint review by the Strategic Advisory Group of Experts on Immunization (SAGE) and the Malaria Policy Advisory Committee (MPAC) in 2015.
RTS,S/AS01 may have an important role in some settings in sub-Saharan Africa, depending on the results in 2014.
RTS,S/AS01 will be evaluated as a possible addition to, and not a replacement for, existing preventive, diagnostic and treatment measures, depending on the results that become available in 2014.