African trypanosomiasis

African trypanosomiasis or sleeping sickness is a tropical disease spread by the bite of an infected tsetse fly. It can be fatal if not treated.

TDR is completing studies of the efficacy and safety of a shortened pentamidine treatment for stage 1 of the disease (3 days instead of 7) and nifurtimox-eflornithine combination treatment for stage 2 of the disease.