Research activities

We fund research designed to find innovative ways to develop new drugs, barriers to the insects and worms that carry the parasites, diagnostics and other tools against infectious diseases in developing countries. We also look for new ways to distribute and increase access to these tools. Work led by researchers from disease endemic countries is always one of our top considerations.

Calls for grant applications or/and letters of interest

Research on innovative approaches for safety monitoring in seasonal malaria chemoprevention

Deadline for submission: 23 December 2014

Research teams from African institutions are invited to submit Letters of Interest (LoI) for research on piloting innovative approaches for safety monitoring in the context of seasonal malaria chemoprevention. Under this call, one or two research teams are expected to be selected for funding for a maximum amount of US$ 75 000 each.

Joint EMRO/TDR small grants scheme for implementation research in infectious diseases of poverty

Deadline for submission: 15 January 2015

Only applicants from the WHO Eastern Mediterranean Region eligible.

This joint call with the Eastern Mediterranean Regional Office of the World Health Organization supports evidence generated from local research for the prevention and control of tropical diseases in the WHO Eastern Mediterranean Region (EMR) countries and takes into account the outcomes of the recent meeting in February 2014 at the regional office: “Integrating Research in Shaping The Future of Health in The EMR”. The call welcomes research which links communicable and tropical diseases of poverty in co-morbidity with non-communicable diseases.

Five calls for applications / letters of interest in collaboration for:
Research on the vulnerability of preventive chemotherapy of helminth infections to emergence of drug resistance

Application deadlines vary from 31 August through 12 January 2015 (see PDF file below for complete details)

TDR is expanding support for research on key determinants of sustained effectiveness of preventive chemotherapy for schistosomiasis, soil transmitted helminths (STH), lymphatic filariasis and onchocerciasis: the probability, potential impact and detection of the emergence of resistance to the drugs used.

Planned research activities to be supported are grouped into two projects:

  • Vulnerability of schistosomiasis, STH, onchocerciasis and lymphatic filariasis control to emergence of drug resistance and its consequences (TDResist, 3 calls, available funding: US$ 260 000)
  • Integrated capacity building and research for ivermectin resistance surveillance and definition of O. volvulus transmission zones by onchocerciasis control programmes (CARIRS, 2 calls, available funding: US$ 400 000).

Grants currently underway or in review

Research on the etiological causes of serious infections in young African infants

Deadline for submission: 25 August 2014

As part of TDR’s focus on improving maternal and childhood health, research teams from African research institutions were invited to submit Letters of Interest (LoI) to undertake a prospective study to investigate the aetiologies of serious infection in young infants in rural areas of Africa. We received 47 applications from 14 different African countries. The applications are being reviewed by an external scientific working group that will evaluate the applications submitted based on scientific merit, relevance to the call and feasibility. The review process is expected to be completed by end of October, when two research teams are expected to be selected for funding for a maximum amount of US$ 140 000 each.

Call for implementation research

Closed: 30 June 2014

The World Health Organization Regional Office for South-East Asia (SEARO), in collaboration with TDR, is accepting proposals on intervention or implementation research on factors required for improved effectiveness, efficiency and appropriate adoption of new and existing interventions and public health delivery models, including innovative approaches to engaging health professionals working on public health both in public and private sectors. Proposals may also offer innovative ways to stimulate a health systems approach and sustain community demand for and participation in major public health interventions. Research on evidence-based and feasible interventions to increase case detection and access to public health facilities can be proposed. All approaches should address key public health challenges related to such infectious diseases of poverty as tuberculosis, malaria, and neglected tropical diseases and other emerging infectious diseases.

Research on the impact of insecticide resistance mechanisms on malaria control failure in Africa

Research teams from African research institutions, in collaboration with National Malaria Control Programmes (NMCPs) were invited to submit proposals to undertake prospective multi-country studies (in at least 3 countries of different epidemiological characteristics per proposal) to assess insecticide resistance mechanisms and their effects on malaria control failure under field conditions in Africa. Application submissions are now closed.

Implementation Research Training Workshop - 7 – 12 July 2013 Gaborone, Botswana

The workshop is part of a module-based toolkit designed to strengthen implementation research capacity in the following areas: contextualizing research, ethics, planning and conducting an IR project, data collection and management, analysis of results, dissemination of findings, and monitoring and evaluation of the uptake of evidence in the health system. Submissions are closed and participants have been selected.

Impact Grant

This is a new short-term grant scheme designed for nationals from low- and middle-income countries. Support under this grant is flexible, based on public health relevance, scientific quality and the feasibility of achieving results within one year. Twenty to thirty new grants (up to US$ 50 000, non-renewed) will be awarded. The awarded recipients will be notified this summer, with funding to begin in September. Application submissions are now closed.

Career Development Fellowships

The highly regarded TDR Career Development Fellowship accepted its fourth round of applications from low- and middle-income country researchers to be placed with leading product development institutions.
Application submissions are now closed.

Climate change impact in Africa on vector-borne diseases

This research is designed to understand the impact of climate change in sub-Saharan Africa on people’s vulnerability to diseases carried by mosquitoes, flies and snails, such as malaria, leishmaniasis and schistosomiasis. With support from the International Development Research Center (IDRC), Canada, $6.8 million will be spent to identify those who are the most vulnerable to social, environmental and climate change, and to develop tools and strategies for adaptation to climate change in Africa.
Application submissions are now closed.

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