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Dengue

Dengue is transmitted by the bite of an Aedes mosquito infected with any one of the four dengue viruses. It occurs in tropical and sub-tropical areas of the world. Symptoms appear 3—14 days after the infective bite. Dengue fever is a febrile illness that affects infants, young children and adults.

Symptoms range from a mild fever, to incapacitating high fever, with severe headache, pain behind the eyes, muscle and joint pain, and rash. There are no specific antiviral medicines for dengue. It is important to maintain hydration. Use of acetylsalicylic acid (e.g. aspirin) and non steroidal anti-inflammatory drugs (e.g. Ibuprofen) is not recommended.

Severe dengue (plasma leakage, severe hemorrhages, organ failure) is a potentially lethal complication, affecting both children and adults. early clinical diagnosis and careful clinical management by experienced physicians and nurses increase survival of patients.

TDR related research

TDR supports research on this disease. For more information, visit these research sections:

  • Vectors, environment and society

Latest news

  • Comments on The Guidance Framework for testing genetically modified mosquitoes under review
    7 March 2013
  • Dengue control support through eco-bio-social approach
    20 February 2013
  • All news on dengue

TDR publications and articles

  • Handbook for clinical management of dengue
    12 November 2012
  • Operational guide for assessing the productivity of Aedes aegypti breeding sites
    31 October 2011
  • Changing Mindsets: Research Capacity strengthening in low and middle-income countries
    1 November 2010
  • All publications on dengue
WHO/TDR/Crump
A doctor palpates the liver of a young boy with dengue in the children's ward.

Dengue transmission

  • Animated life-cycle of Aedes aegypti (Flash)
    swf, 149kb

Related WHO information

  • Fact sheet: Dengue and dengue haemorrhagic fever
  • Global Alert and Response (GAR)
  • Disease Outbreak News: dengue fever
  • DengueNet database and geographic information system
  • International travel and health
    Publication on travel risks, precautions and vaccination requirements

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Special Programme for Research and Training in Tropical Diseases (TDR)