Rabies is a neglected zoonotic disease (a disease that is transmitted from animals to humans), caused by the rabies virus of the genus Lyssavirus. With the exception of Antarctica, the disease is present on all continents. The highest case incidence occurs in Asia and Africa, where rabies potentially threatens over 4.5 billion people.
Rabies is a 100% vaccine-preventable disease. However, despite the availability of tools to manage the disease, rabies still kills 35 000 to 59 000 humans every year. The disease disproportionately affects poor, low-resource communities, particularly children with 4 out of every 10 human deaths by rabies occurring in children younger than 15 years.
150Human rabies is present in 150 countries and territories and on all continents, except for AntarcticaWHO Expert Consultation on Rabies (TRS 982)
100%Rabies is 100% preventable by vaccination, yet continues to killRabies: 100 per cent fatal, 100 per cent preventable
60–80%cost savings associated with use of intradermal vs intramuscular vaccines for prophylaxisWHO recommendations for post-exposure prophylaxis