Rabies is a neglected zoonotic disease (a disease that is transmitted from animals to humans), caused by the rabies virus of the genus Lyssavirus. With the exception of Antarctica, the disease is endemic on all continents. The highest case incidence occurs in Asia and Africa, where rabies potentially threatens over 3 billion people.
Rabies is a 100% vaccine-preventable disease. However, despite the availability of tools to manage the disease, rabies prevails to cause tens of thousands of deaths every year. The disease disproportionately affects poor, low-resource communities, particularly children with 4 out of every 10 human deaths by rabies occurring in children younger than 15 years.
150With the exception of Antarctica, rabies is endemic within 150 countries and territories, on all continentsWHO Expert Consultation on Rabies (TRS 982)
Highrisk of contracting rabies, particularly in rural areas of endemic countriesGlobal distribution of risk to humans of contracting rabies, 2011
60–80%cost savings associated with use of intradermal vs intramuscular vaccines for prophylaxisWHO recommendations for post-exposure prophylaxis