Mental health

Antipsychotics and mood stabilizers (lithium, valproate, or carbamazepine) for maintenance treatment of bipolar disorder

[Updated 2015]


Lithium or valproate or certain second-generation antipsychotics (aripiprazole, olanzapine, paliperidone extended release, quetiapine, and risperidone long acting injection release) can be offered for the maintenance treatment of bipolar disorder. If treatment with one of these agents is not feasible, first-generation antipsychotics or carbamazepine may be used. Maintenance treatment should be offered in primary health care settings under supervision of a specialist.
Strength of recommendation: CONDITIONAL
Quality of evidence: LOW