Antiepileptic drug treatment after first unprovoked seizure
Question 8: Should antiepileptic drug treatment be started after first unprovoked seizure in non-specialist health settings?
- Population: adults and children with a first unprovoked seizure
- Interventions: antiepileptic drug treatment offered after first seizure
- antiepileptic drug treatment offered only after a seizure recurrence
- time to first seizure
- time to 2-year remission
- adverse effects
- quality of life.
Antiepileptic drugs should not be routinely prescribed to adults and children after a first unprovoked seizure. In adults and children with a high risk of recurrence (e.g. presence of neurological deficit, associated handicaps), referral should be made to specialist setting for further assessment.
Strength of recommendation: STRONG