Mental health

Pharmacological interventions (antidepressants) for people with dementia who have associated depression

[2015]

Recommendation(s)

In people with dementia and severe depression, or when psychosocial interventions prove ineffective, the use of selective serotonin reuptake inhibitors (SSRIs) (but not tricyclic antidepressants [TCAs]) may be considered.

In people with dementia and mild to moderate depression, antidepressants should not be offered as a first-line treatment.

Strength of recommendation: CONDITIONAL
Quality of evidence: LOW