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Fact sheet
Updated July 2016

Key facts

  • Trachoma is a disease of the eye caused by infection with the bacterium Chlamydia trachomatis.
  • It is known to be a public health problem in 42 countries, and is responsible for the blindness or visual impairment of about 1.9 million people. Just over 200 million people live in trachoma endemic areas and are at risk of trachoma blindness.
  • Blindness from trachoma is irreversible.
  • Infection spreads through personal contact (via hands, clothes or bedding) and by flies that have been in contact with discharge from the eyes or nose of an infected person. With repeated episodes of infection over many years, the eyelashes may be drawn in so that they rub on the surface of the eye, with pain and discomfort and permanent damage to the cornea.
  • Resolution WHA51.11 adopted by the World Health Assembly in 1998 targets the global elimination of trachoma as a public health problem by 2020.
  • The elimination strategy is encapsulated by the acronym “SAFE”: Surgery for advanced disease, Antibiotics to clear C. trachomatis infection, and Facial cleanliness and Environmental improvement to reduce transmission.
  • In 2015, more than 185 000 people received surgical treatment for advanced disease, and 56 million people were treated with antibiotics for trachoma.

Trachoma is the leading infectious cause of blindness worldwide. It is caused by an obligate intracellular bacterium called Chlamydia trachomatis. The infection is transmitted through contact with eye and nose discharge of infected people, particularly young children who harbour the principal reservoir of infection. It is also spread by flies which have been in contact with the eyes and noses of infected people.

Clinical characteristics and morbidity

In areas where trachoma is endemic, active (inflammatory) trachoma is common among preschool-aged children, with prevalence rates which can be as high as 60–90%. Infection becomes less frequent and shorter in duration with increasing age. Infection is usually acquired when living in close proximity to others with active disease, and the family is the main setting for transmission. An individual’s immune system can clear a single episode of infection, but in endemic communities, re-acquisition of the organism occurs frequently.

After years of repeated infection, the inside of the eyelid can become so severely scarred (trachomatous conjunctival scarring) that it turns inwards and causes the eyelashes to rub against the eyeball (trachomatous trichiasis), resulting in constant pain and light intolerance; this and other alterations of the eye can lead to scarring of the cornea. Left untreated, this condition leads to the formation of irreversible opacities, with resulting visual impairment or blindness. The age at which this occurs depends on several factors including local transmission intensity. In very highly endemic communities, it can occur in childhood, though onset of visual impairment between the ages of 30 and 40 years is more typical.

Visual impairment or blindness results in a worsening of the life experience of affected individuals and their families, who are normally already amongst the poorest of the poor. Women are blinded up to 4 times as often as men, probably due to their close contact with infected children and the resulting greater frequency of infection episodes.

Environmental risk factors influencing the transmission of the disease include:

  • poor hygiene
  • crowded households
  • water shortage
  • inadequate latrines and sanitation facilities.


Trachoma is hyperendemic in many of the poorest and most rural areas of 42 countries of Africa, Central and South America, Asia, Australia and the Middle East.

It is responsible for the blindness or visual impairment of about 1.9 million people. It causes about 1.4% of the global total of blind individuals.

Overall, Africa remains the most affected continent, and the one with the most intensive control efforts. In 2015, in the 29 countries of WHO’s Africa Region in which trachoma is known to be a public health problem, nearly 176 000 people with trichiasis were given operations (95% of the global total operated), and more than 54 million people were treated with antibiotics (97% of the global total treated) for trachoma.

As of 1 March 2016, 7 countries had reported achieving elimination goals, which signifies a major milestone in the campaign to eliminate trachoma. These countries are: China, Gambia, Ghana, the Islamic Republic of Iran, Morocco, Myanmar and Oman. In November 2012, Oman was acknowledged by WHO to have eliminated trachoma.

Economic impact

The burden of trachoma on affected individuals and communities is enormous. The economic cost in terms of lost productivity from blindness and visual impairment is estimated at between US$ 2.9 billion and US$ 5.3 billion annually, increasing to US $8 billion when trichiasis is included.

Prevention and control

Elimination programmes in endemic countries are being implemented using the WHO-recommended SAFE strategy. This consists of:

  • Surgery to treat the blinding stage of the disease (trachomatous trichiasis);
  • Antibiotics to clear infection, particularly mass drug administration of the antibiotic azithromycin, which is donated by the manufacturer to elimination programmes, through the International Trachoma Initiative;
  • Facial cleanliness; and
  • Environmental improvement, particularly improving access to water and sanitation.

Most endemic countries have agreed to accelerate the implementation of this strategy to achieve their respective elimination targets, all by the year 2020.

Data reported to WHO by Member States for 2015 show that more than 185 000 people with trachomatous trichiasis were provided with corrective surgery in that year, and 56 million people in endemic communities were treated with antibiotics to eliminate trachoma.

Elimination efforts need to continue to satisfy the target set by World Health Assembly resolution WHA 51.11, which is elimination of trachoma as a public health problem by 20201. Particularly important will be the full engagement of other sectors involved in water, sanitation and socioeconomic development.

WHO response

WHO adopted the SAFE strategy in 1993. Its mandate is to provide technical leadership and coordination to international efforts aiming to eliminate trachoma as a public health problem.

In 1996, WHO launched the Alliance for the Global Elimination of Trachoma by 2020 (GET2020). GET2020 is a partnership which supports implementation of the SAFE strategy by Member States, and the strengthening of national capacity through epidemiological surveys, monitoring, surveillance, project evaluation, and resource mobilization.

From 2012 to 2015, WHO helped to lead the Global Trachoma Mapping Project, which provided baseline survey data for 1546 suspected endemic districts in 29 countries, facilitating the launch of interventions where they are required. In July 2016, WHO, the International Trachoma Initiative, RTI International, and Sightsavers launched Tropical Data, a WHO-led epidemiological survey support service to assist national neglected tropical disease programmes.

1 Elimination of trachoma as a public health problem is defined as: (i) a prevalence of trachomatous trichiasis “unknown to the health system” of less than 1 case per 1000 total population; and (ii) a prevalence of trachomatous inflammation-follicular in children aged between 1–9 years of less than 5%, in each formerly endemic district.


Global elimination of blinding trachoma

Tropical Data