Preventive therapies

A group of Somali mothers and children standing near their homes.
Sarah Hoibak/MENTOR

Preventive chemotherapies are key elements of the comprehensive package of malaria prevention and control measures recommended by WHO. WHO-recommended preventive therapies include intermittent preventive treatment of pregnant women (IPTp), intermittent preventive treatment of infants (IPTi), and seasonal malaria chemoprevention (SMC). The objective of these interventions is to prevent malarial illness by maintaining therapeutic drug levels in the blood throughout the period of greatest malarial risk.

Overview of preventive therapies

WHO recommends a full antimalarial treatment course to be given to pregnant women, infants and children, to prevent the consequences of malaria infection.

Intermittent preventive treatment in pregnancy (IPTp)

WHO recommends the administration of IPTp in pregnant women in areas of moderate to high malaria transmission in Africa.

Intermittent preventive treatment in infants (IPTi)

WHO recommends the administration of IPTi in infants in areas of moderate to high malaria transmission in Africa. The administration of the therapy should correspond to the routine vaccination schedule.

Seasonal malaria chemoprevention (SMC)

WHO recommends the administration of SMC in children under five years of age in areas with highly seasonal malaria transmission in the Sahel sub-region of sub-Saharan Africa.

Key documents

World Malaria Report 2013

This report contains the latest available data on malaria policies, interventions and trends in all endemic countries.

Contact us

Global Malaria Programme
World Health Organization
20 Avenue Appia
1211 Geneva 27
Tel: +41 22 791 2533
Fax: +41 22 791 4824