Listing of IPCS publications and projects on risk assessment methodology
A consolidated list is provided below of published Environmental Health Criteria and those in development together with published documents from the IPCS Harmonization project and those relating to new and emerging issues.
It is organized alphabetically by topic. Projects and documents marked with an asterisk (*) are in development.
The words [new window] indicate a direct link is available to the IPCS INCHEM database. The document is available in HTML.
A to E
Biomarkers: IPCS Guidelines for the monitoring of genotoxic effects of carcinogens in humans. Albertini RJ, Anderson D, Douglas GR, Hagmar L, Hemminki K, Merlo F, Natarajan AT, Norppa H, Shuker DE, Tice R, Waters MD, Aitio A. Mutatation Research. 2000 Aug;463(2):111-72.
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Acute reference dose: Guidance on setting of acute reference dose (ARfD) for pesticides
pdf, 310kb - Aged Population: Principles for evaluating chemical effects on the aged population (EHC No. 144, 1993) - full text [new window]
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Autoimmunity: Principles and Methods for Assessing Autoimmunity Associated with Exposure to Chemicals (EHC No. 236, 2006)
pdf, 2.02Mb - Biomarkers: Biomarkers and risk assessment: Concepts and principles (EHC No. 155, 1993) - full text [new window]
- Biomarkers: Biomarkers in risk assessment: Validity and validation (EHC No. 222, 2001) - full text [new window]
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Carcinogens: IPCS Conceptual Framework for Cancer Risk Assessment (Harmonization project)
pdf, 73kb - Carcinogens: Summary report on the evaluation of short-term tests for carcinogens (EHC No. 47, 1985), Collaborative study of in vivo tests) (1985) - full text [new window]
- Carcinogenic chemicals: Guide to short-term tests for detecting mutagenic and carcinogenic chemicals (ICPEMC) (EHC No. 51, 1985) - full text [new window]
- Carcinogens: Summary report on the evaluation of short-term tests for carcinogens (EHC No. 109, 1990) Collaborative study on in vivo tests) (1990) - full text [new window]
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Children: Principles for evaluating health risks in children associated with exposure to chemicals (EHC No. 237, 2006)
pdf, 3.57Mb - Children: Principles for evaluating health risks from chemicals during infancy and childhood: The need for a special approach (EHC No. 59, 1986) - full text [new window]
- Cross-Species Extrapolation: Draft Guidance Document for the Use of Chemical-Specific Adjustment Factors (CSAFs) for Interspecies Differences and Human Variability in Dose/Concentration - Response Assessment (July 2001) (Harmonization project).
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Dermal Absorption
pdf, 1.72Mb - Diseases of suspected chemical etiology: Principles of studies on diseases of suspected chemical etiology and their prevention (EHC No. 72, 1987) - full text [new window]
- Dose-Response modelling: Principles for Modelling Dose-Response for the Risk Assessment of Chemicals
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Elemental Speciation in Human Health Risk Assessment (EHC No. 234, 2006)
pdf, 1.76Mb - Environmental Epidemiology: Guidelines on studies in Environmental Epidemiology (EHC No. 27, 1983) - full text [new window])
- Essential Trace Elements: Principles and methods for the assessment of risk from essential trace elements (EHC No. 228, 2002) - full text [new window]
- Evaluating the toxicity of chemicals: Evaluating the toxicity of chemicals - Principles and methods for (EHC No. 6, Part I (1978)) - full text [new window])
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Exposure Assessment: Glossary of Exposure Assessment-Related Terms: A compilation (November 2001)
pdf, 287kb
(Harmonization project)
F to N
- Food: Principles for the safety assessment of food additives and contaminants in food (EHC No. 70, 1987) - full text [new window]
- Food: Principles for the toxicological assessment of pesticide residues in food (EHC No. 104, 1990) - full text [new window]
- * Food: Project to update the principles and methods for the assessment of chemicals in food
- * Food: Nutrients - Scientific Principles for Nutrient Risk Assessment
- Genetic Effects: Guidelines for the study of genetic effects in human populations (EHC No. 46, 1985) - full text [new window]
- Guidance values for health-based exposure limits: Assessing human health risks of chemicals: Derivation of guidance values for health-based exposure limits (EHC No. 170, 1994) - full text [new window]
- Human health risks: Principles for the assessment of risks to human health from exposure to chemicals (EHC No. 210, 1999) - full text [new window]
- Hypersensitization: Principles and methods for assessing allergic hypersensitization associated with exposure to chemicals (EHC No. 212, 1999) - full text [new window]
- Immunotoxicity: Principles and methods for assessing direct immunotoxicity associated with exposure to chemicals EHC No. 180, 1996) - full text [new window and associated corrigendum]
- Insecticide-treated mosquito nets: A generic risk assessment model for insecticide treatment and subsequent use of mosquito nets
- Mutagenicity testing for chemical risk assessment: update of the WHO/IPCS Harmonized Scheme
N to Z
- Nephrotoxicity: Principles and methods for the assessment of nephrotoxicity associated with exposure to chemicals (EHC No. 119, 1991) - full text [new window]
- Neurotoxicity: Principles and methods for the assessment of neurotoxicity associated with exposure to chemicals. EHC No. 60, 1986) - full text [new window]
- Neurotoxicity: Integrated approach to the assessment of neurotoxicity of chemicals (EHC No. 223, 2001) - full text [new window]
- Reproduction: Principles for evaluating health risks to progeny associated with exposure to chemicals during pregnancy (EHC No. 30, 1984) - full text, new window)
- Reproduction: Principles for evaluating health risks to reproduction associated with exposure to chemicals (EHC No. 225, 2001) - full text [new window]
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Reproduction: Devtox web site
A web-based resource on developmental toxicology (Harmonization project) - Safety Testing: Quality management for chemical safety testing (EHC No. 141, 1992) - full text [new window]
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Terminology: Descriptions of selected key generic terms used in chemical hazard/risk assessment
Joint IPCS/OECD Project on the Harmonization of Chemical Hazard/Risk Assessment Terminology (Harmonization project) -
Terminology: IPCS Glossary of Exposure Terminology (Harmonization project)
pdf, 287kb - Toxicokinetic Studies: Principles of toxicokinetic studies (EHC No. 57, 1986) - full text [new window]
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Transgenic animal mutagenicity assays (EHC No. 233, 2006)
pdf, 2.04Mb -
Uncertainty and Data Quality in Exposure Assessment
pdf, 1.61Mb
The words [new window] indicate a direct link is available to the IPCS INCHEM database. The document is available in HTML.