Global action plan for influenza vaccines

Global Action Plan for Influenza Vaccines (GAP)

Global Action Plan for Influenza Vaccines (GAP) is a comprehensive strategy to reduce the present global shortage of influenza vaccines for seasonal epidemics and pandemic influenza in all countries of the world through three major approaches:
- Increase in seasonal vaccine use
- Increase in vaccine production capacity
- Research and development

GAP was launched in 2006 and further refined in 2011.

Objective 1: increase in seasonal vaccine use

The first GAP approach is to encourage countries to increase their seasonal vaccine use.
Increased use of seasonal influenza vaccine will reduce disease burden of seasonal influenza infections, contribute towards the preparedness of countries to respond to an eventual pandemic and motivate industry to develop greater capacity for manufacturing vaccines.

Objective 2: increase in vaccine production capacity

The second GAP approach concentrates on increasing production capacity for pandemic vaccines without expectation for a commensurate increase in the demand for seasonal vaccine.
Short term – produce enough vaccine to immunize two billion people; this vaccine should be available on the market six months after transfer of the vaccine prototype strain to industry.
Medium and long term – produce enough vaccine to immunize the world’s population (6.7 billion).

Objective 3: research and development

The third GAP approach encourages to use new technologies to develop more potent and effective influenza vaccines that are:
(a) capable of inducing protective responses after one dose, and/or
(b) induce broad-spectrum and long-lasting immunity against both seasonal and pandemic influenza strains.

About GAP:

What's new:

  • 26 February 2015

    WHO recommendation composition influenza virus vaccines northern hemisphere 2015-2016

    The WHO recommendation on the composition of influenza virus vaccines for use in the northern hemisphere 2015-2016 was announced following a 3-day WHO Consultation with Advisers from the WHO CCs and WHO ERLs. WHO recommends that influenza vaccines for use in the 2015-2016 influenza season (northern hemisphere winter) contain the following: – an A/California/7/2009 (H1N1)pdm09-like virus; – an A/Switzerland/9715293/2013 (H3N2)-like virus; – a B/Phuket/3073/2013-like virus. It is recommended that quadrivalent vaccines contain the above three viruses and a B/Brisbane/60/2008-like virus.

  • 16 - 17 December 2014

    Meeting on Live Attenuated Influenza Vaccines in Low and Middle Income Countries

    A multidisciplinary expert meeting reviewed available evidence of public health benefits and potentially associated risks of the use of live attenuated influenza vaccines (LAIV) in young children and discussed scientific, regulatory, and ethical perspectives of clinical studies with LAIV in children under 2 years of age.

  • 24 May 2014

    GAP Progress Report: 2006-2013

    This is the first GAP global progress report that provides details on key highlights for the period from 2006, when GAP was launched, to September 2013. It is anticipated that regular updates will follow approximately every two years.

Contact us:

World Health Organization
Global Action Plan for Influenza Vaccines (GAP)
20, avenue Appia
1211 Geneva 27, Switzerland
gap_flu_vaccine@who.int

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