Influenza

Recommended composition of influenza virus vaccines for use in the 2013-14 northern hemisphere influenza season

21 February 2013

It is recommended that trivalent vaccines for use in the 2013-14 influenza season (northern hemisphere winter) contain the following:

  • an A/California/7/2009 (H1N1)pdm09-like virusa;
  • an A(H3N2) virus antigenically like the cell-propagated prototype virus A/Victoria/361/2011b*;
  • a B/Massachusetts/2/2012-like virus.

It is recommended that quadrivalent vaccines containing two influenza B viruses contain the above three viruses and a B/Brisbane/60/2008-like virusc.

a A/Christchurch/16/2010 is an A/California/7/2009-like virus;
b A/Texas/50/2012 is an A(H3N2) virus antigenically like the cell-propagated prototype virus A/Victoria/361/2011;
c B/Brisbane/33/2008 is a B/Brisbane/60/2008-like virus.

* It is recommended that A/Texas/50/2012 is used as the A(H3N2) vaccine component because of antigenic changes in earlier A/Victoria/361/2011-like vaccine viruses (such as IVR-165) resulting from adaptation to propagation in eggs.

For more information

Candidate viruses for vaccine development and production for the northern hemisphere 2013-14

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