Prevention of mother-to-child transmission of HIV: selection and use of nevirapine
Technical notes
Reference Number: WHO/HIV_AIDS/2001.03
A technical consultation on the prevention of mother-to-child transmission (MTCT) of HIV was convened by WHO in Geneva from 11-13 October 2000 on behalf of the United Nations Interagency Task Team on Mother-to-Child Transmission of HIV Infection. Participants reviewed available evidence on the efficacy and safety of antiretroviral prophylactic regimens used for MTCT-prevention in resource-limited settings. They concluded that all the regimens that have been shown to be effective in controlled clinical trials can be recommended for use in MTCT-prevention programmes in such settings. These regimens include zidovudine alone, zidovudine plus lamivudine, and nevirapine alone.The experts agreed there was no longer any justification to restrict use of any of these regimens to pilot project or research settings.