Developing the 2013 WHO consolidated antiretroviral guidelines
Series of articles and commentaries from AIDS supplement: 2013 WHO consolidated guidelines on the use of antiretroviral drugs: evidence and implementation
The 2013 ‘Consolidated guidelines on the use of antiretroviral (ARV) drugs for treating and preventing HIV infection’, released in July 2013, are the latest and most comprehensive of a series of important guidelines on antiretroviral therapy (ART) over the last decade from the World Health Organization (WHO).
In this special supplement of AIDS, we present a series of thirteen articles and five commentaries covering key aspects of the consolidated guidelines: the process, evidence base, recommendations and guidelines implementation.
In this first article, we describe the WHO process and methodology of developing these guidelines. This is followed by seven selected systematic reviews that provided the evidence base for specific recommendations.
Access all articles and commentaries
- Antiretroviral therapy initiation criteria in low resource settings – from ‘when to start’ to ‘when not to start’
- Early initiation of antiretroviral therapy in HIV-infected adults and adolescents: a systematic review
- Antiretroviral treatment for pregnant and breastfeeding women – the shifting paradigm
- Safety of efavirenz in the first trimester of pregnancy: an updated systematic review and meta-analysis
- When to start and what to use in children – recommendations and rationale
- Optimization of antiretroviral therapy in HIV-infected children under 3 years of age: a systematic review
- The monitoring of adults and children on antiretroviral therapy in the 2013 WHO consolidated ARV guidelines
- Optimal strategies for monitoring response to antiretroviral therapy in HIV-infected adults, adolescents, children and pregnant women: a systematic review
- Predicting treatment failure in adults and children on antiretroviral therapy: a systematic review of the performance characteristics of the 2010 WHO immunologic and clinical criteria for virologic failure
- Operational Guidance in the 2013 WHO consolidated antiretroviral guidelines
- Improving antiretroviral therapy scale-up and effectiveness through service integration and decentralization
- Interventions to improve adherence to antiretroviral therapy: a rapid systematic review
- Community and service provider views to inform the 2013 WHO consolidated antiretroviral guidelines: key findings and lessons learnt
- Adoption of national recommendations related to use of antiretroviral therapy before and shortly following the launch of the 2013 WHO consolidated guidelines
- The impact and cost of the 2013 WHO recommendations on eligibility for antiretroviral therapy