Global situation and trends: In 2012, an estimated 8.6 million people developed TB and 1.3 million died from the disease (including 320 000 deaths among HIV-positive people). The rate of new TB cases has been falling worldwide for about a decade, achieving the Millennium Development Goal to reverse the spread of TB by 2015. Globally, the TB mortality rate has fallen by 45% since 1990 and the Stop TB Partnership target of a 50% reduction by 2015 is within reach. Although most TB cases and deaths occur among men, the burden of disease is high among women. In 2012, an estimated 410 000 women died from TB (250 000 among HIV-negative women and 160 000 among HIV-positive women). There were also an estimated 74 000 TB deaths among HIV-negative children.