Optimal timing of cord clamping for the prevention of iron deficiency anaemia in infants
At the time of birth, an infant is still attached to the mother via the umbilical cord, which is part of the placenta. The infant is usually separated from the placenta by clamping the umbilical cord.
Early cord clamping is generally carried out in the first 60 seconds after birth, whereas later cord clamping is carried out more than one minute after the birth or when cord pulsation has ceased.
Delaying cord clamping allows blood flow between the placenta and neonate to continue, which may improve iron status in the infant for up to six months after birth. This may be particularly relevant for infants living in low-resource settings with reduced access to iron-rich foods.
Late cord clamping approximately (one to three minutes after birth) is recommended for all births while initiating simultaneous essential newborn care.
Early cord clamping (less than one minute after birth) is not recommended unless the neonate is asphyxiated and needs to be moved immediately for resuscitation.
Systematic reviews used to develop guidelines
- Effect of timing of umbilical cord clamping of term infants on maternal and neonatal outcomes
- Effect of timing of umbilical cord clamping and other strategies to influence placental transfusion at preterm birth on maternal and infant outcomes
Related systematic reviews
Timing of umbilical cord clamping in term and preterm deliveries and infant and maternal outcomes: a systematic review of randomized controlled trials
Late umbilical cord-clamping as an intervention for reducing iron deficiency anaemia in term infants in developing and industrialised countries: a systematic review
Late vs early clamping of the umbilical cord in full-term neonates: systematic review and meta-analysis of controlled trials