Health system strengthening and hypertension awareness, treatment and control: data from the China Health and Retirement Longitudinal Study
Xing Lin Feng a, Mingfan Pang a & John Beard b
a. Department of Health Policy and Administration, School of Public Health, Peking University, Beijing, 100191, China.
b. Department of Ageing and Life Course, World Health Organization, Geneva, Switzerland.
Correspondence to Xing Lin Feng (e-mail: email@example.com).
(Submitted: 13 May 2013 – Revised version received: 13 August 2013 – Accepted: 17 August 2013 – Published online: 10 September 2013.)
Bulletin of the World Health Organization 2014;92:29-41. doi: http://dx.doi.org/10.2471/BLT.13.124495
Cardiovascular and other noncommunicable diseases are currently responsible for two thirds of global mortality.1,2 Universal health coverage may allow great improvements in the control of such diseases3,4 but the best way to achieve such coverage, especially in low- and middle-income countries, remains unclear.5
Hypertension is a consistent and independent risk factor for cardiovascular and kidney diseases and stroke.6 It is also very common, its global prevalence being about 40%.2 Hypertension, which plays a part in approximately 55% of the global mortality caused by cardiovascular diseases and in 7% of all disability-adjusted life years,7 could be managed at fairly low cost, even in resource-poor settings.8–10 In the developed world, more than 80% of people with hypertension are aware of their condition and receiving treatment.11–13 However, the health systems in most developing countries fail to detect and manage hypertension effectively.14,15
In China, the overall prevalence of hypertension rose substantially between 2002 and 2010 – from around 20% to 34%.16–18 Unfortunately, the management of hypertension in China has been ineffective for many years. In 2010, for example, only 35.7% of hypertensive individuals were aware of their condition and fewer than 18% of such individuals were effectively controlling their hypertension.17–19 It has been estimated that hypertension was associated with 20% of the deaths recorded in China in 2005, including 2.33 million – nearly 80% – of the deaths from cardiovascular disease.20 Hypertension not only causes premature death; it may also add to household costs. In a study conducted in rural China, for example, it was estimated that 4.1% of households suffered impoverishment as a result of hypertension.21
The prevention and control of noncommunicable diseases have been on China’s policy agenda for decades.22 In 2009, however, there was a huge reform of the national health system. The main aim of this reform was to attain universal coverage with affordable and equitable basic health care.23,24 Three of the five pillars of the reform – a national programme of primary health care, a national essential medicine system and universal health insurance – are directly linked to the management of noncommunicable diseases.
Each year, the national programme of primary health care now spends 25 yuan per capita – or about 6.3 billion United States dollars in total – on community health-care providers. These providers work in urban community health-care centres or rural township hospitals and deliver a defined package of health care that includes the management of noncommunicable diseases.23–25 The centres for community health care are responsible for establishing a health record and providing free health examinations – that include the measurement of blood pressure – for every person living in their catchment areas. The centres also provide advice on anti-hypertensive medication and hypertension control whenever appropriate. They should have access to more than 400 essential medicines, including various anti-hypertensive drugs such as beta blockers and calcium channel blockers. Provision of these medicines is heavily subsidized by the Chinese government on a non-profit basis.26 Development of the two national programmes (primary health care and essentials medicine system) was expected to lead to substantial improvements in the detection, treatment and control of hypertension.
Universal health insurance coverage was another goal of the health system reform launched in 2009. The achievement of this goal is slightly hampered by the number of health insurance schemes that exist in China and by the variation in the type and extent of the coverage offered by these schemes. In urban China, the Employee Basic Medical Insurance Scheme covers some of the employed. Some government employees are – or were – covered by the Government Insurance Scheme, while some other urban dwellers are covered by the Urban Resident Basic Medical Insurance Scheme. In rural areas, a New Cooperative Medical Scheme has been developed. Although health insurance has already become almost universal in China,24,25 most of the population relies either on the Urban Resident Basic Medical Insurance Scheme or the New Cooperative Medical Scheme. These schemes focus on inpatient expenses and offer almost no reimbursement for outpatient costs.25 Individuals who have to pay for outpatient care from their own pockets may be reluctant to seek medical care or advice and may never be checked for hypertension or other noncommunicable disorders until they are very ill and facing catastrophic expenditure.27–29
We investigated the prevalence, awareness, treatment and control of hypertension in China by using data from a national survey that was conducted in 2011–2012. The results indicate that changes in health financing and insurance may improve the detection and management of hypertension in China.
We used data collected in the China Health and Retirement Longitudinal Study (CHARLS) of Chinese people aged 45 years or older.30,31 The data were collected in a survey in which four-stage, stratified, cluster sampling was used to select eligible individuals. In the first stage, 150 county-level units from 28 provinces were selected to give a mix of urban and rural settings and a wide variation in the level of economic development. Three primary sampling units – administrative villages (cun) in rural areas and neighbourhoods (shequ) in urban areas – were then chosen in each selected county-level unit. All of the dwellings in each selected primary sampling unit were then outlined on Google Earth maps using the “CHARLS-GIS” software package that was specifically designed for the survey. Finally, for the present investigation, 24 of the mapped households in each primary sampling unit were randomly selected. If a selected household had more than one member aged 45 years or older, one such member – randomly chosen – and his or her spouse if also aged 45 years or older were selected as subjects of the survey. Overall, 17 708 individuals were investigated.30
A structured questionnaire with several main sections was used to collect data from each subject. One section was used to record height, weight and blood pressure. Each subject’s systolic and diastolic blood pressures were recorded three times by a trained nurse using an HEM-7112 electronic monitor (Omron, Kyoto, Japan). The mean values for each subject were then calculated but only given to the subjects once the interviews had ended. The interviewees were asked if they had hypertension and whether they were taking any form of anti-hypertensive medication, including Chinese traditional medicines. A subject was considered hypertensive if he or she had a mean systolic blood pressure of ≥ 140 mmHg, a mean diastolic blood pressure of ≥ 90 mmHg and/or was already taking anti-hypertensive medication.2 A systolic blood pressure of ≥ 160 mmHg or a diastolic blood pressure of ≥ 100 mmHg was considered indicative of stage 2 hypertension, while corresponding values of ≥ 180 and ≥ 110 mmHg were considered indicative of stage 3.32 Hypertensive persons who had previously received a doctor’s diagnosis of hypertension or simply claimed to be hypertensive were considered to be aware of their hypertension. Hypertensive persons who claimed to be receiving any form of anti-hypertensive medication were considered to have treated hypertension. Hypertensive persons whose systolic blood pressure was < 140 mmHg or whose diastolic blood pressure was < 90 mmHg – or both – were considered to be controlling their hypertension well.14
Subjects were asked if they belonged to a health-insurance scheme and, if so, to identify the scheme. The schemes were separated into those providing the costs of outpatient care – the Employee Basic Medical Insurance Scheme and the Government Insurance Scheme – and those that contributed nothing or almost nothing to the costs of outpatient care – the Urban Resident Basic Medical Insurance Scheme or the New Cooperative Medical Scheme. All of the respondents with anthropometric measurements had health insurance.
One section of the questionnaire investigated the socioeconomic status of each subject and his or her modifiable indicators of hypertension risk. The socioeconomic factors investigated were setting, geographical region, sex, age, marital status, level of education and household income. Each subject was classified as a long-term urban resident, a long-term rural resident or a rural resident who had moved into an urban area. Level of education was categorized as illiterate, primary education only, secondary education but no higher, or educated to at least college level. Household income was split into five quintiles. The modifiable risk factors that we considered were body mass index, how often the subject drank alcohol in a month, whether the subject smoked tobacco every day, the subject’s level of exercise, the number of times in the previous year that the subject’s blood pressure had been measured, and whether the subject had had a health examination in the previous two years. A subject was categorized as “active” if he or she engaged in 30 minutes of moderate activity at least five times per week or in 20 minutes of vigorous activity at least three times per week. Those who engaged in < 10 minutes of continuous exercise each week were categorized as “sedentary”. All other subjects were considered to be “less active”.2
In the results, we report both weighted and unweighted proportions. The weights take account of the national representativeness of the results and the missing anthropometric measurements.31 Multilevel Poisson regression was used – with allowance for the sample stratification and clustering at village and household level – to determine – for various groups – the crude and adjusted relative risks (RRs) for lack of awareness of hypertension in a hypertensive individual, lack of anti-hypertensive treatment of a hypertensive individual and failure of a hypertensive individual to control his or her hypertension well. Poisson regression was used because we wanted to compute RRs rather than odds ratios.33 Potential explanatory variables were added individually to determine their effects on the magnitudes of the RRs.
Although 17 708 individuals were surveyed, full data were only available for 13 707 of them (Fig. 1). The proportion of subjects with any missing observations appeared unaffected by age, sex, level of education, setting, household income or marital status.31 Although 22.7% of the interviewees who reported hypertension had missing information, the corresponding value for those not reporting hypertension – 20.8% – was similar.
Fig. 1. Flowchart showing the selection of the subjects who were included in the final analysis in study of hypertension prevalence and control in China, 2011–2012
Table 1 summarizes the background characteristics of the 13 707 subjects who were included in the final analysis. The weighted proportions were similar to the unweighted values. Most of the subjects lived in urban areas and were literate. Most belonged to health insurance schemes that did not cover the costs of outpatient care.
Of the 13 707 individuals whose data were analysed, 5295 (38.6%) were found to have hypertension, although the more severe forms of hypertension – stages 2 and 3 – were relatively rare (Table 2). More than 40% of the individuals found to have hypertension were unaware that they were hypertensive, more than half were not receiving any form of anti-hypertensive medication and < 20% were controlling their hypertension well (Table 2). The prevalence of hypertension was higher among urban than among rural residents – with weighted values of 44.8% and 37.1%, respectively – but, compared with their urban counterparts, rural hypertensive subjects were slightly less likely to be aware of their hypertension and to be on medication. There were no differences between urban and rural subjects in terms of hypertension control (Table 2).
Many of the subjects were overweight (weighted percentage: 26.5%) or obese (6.1%) and more than one in every five of them drank alcohol at least twice per month or smoked every day (Table 2). Most of the subjects lived sedentary lives, most had not had their blood pressure measured in the previous year, and most had not had a health examination in the previous 2 years (Table 2). In terms of the prevalences of these modifiable risk factors, the surveyed subjects in urban areas were similar to those in rural areas (Table 2).
When the subjects were divided into five age groups – < 50, 50–59, 60–69, 70–79 and ≥ 80 years – the prevalence of hypertension in every age group was found to be slightly higher among the members of health insurance schemes that covered the costs of outpatient care than among the members of other health insurance schemes (Fig. 2). However, the three aspects of the management of hypertension that we investigated – awareness, treatment and effective control – were also more common among the members of health insurance schemes that covered the costs of outpatient care (Fig. 3).
Fig. 2. Prevalence of hypertension, by age group and type of health insurance, China, 2011–2012
Fig. 3. Awareness, treatment and control of hypertension, by age group and type of health insurance, 2011–2012
In terms of the awareness (Table 3) and treatment (Table 4) of hypertension, the differences seen between urban residents and rural residents were smaller than – and could be fully explained by – those seen between the two types of insurance coverage. After adjusting for sex, age, marital status, level of education and household income, the hypertensive members of health insurance schemes that covered the costs of outpatient care appeared to be more likely to be aware of their disorder (RR: 1.357; 95% confidence interval, CI: 1.139–1.616) and more likely to be receiving anti-hypertensive treatment (RR: 1.258; 95% CI: 1.010–1.471) than the other hypertensive subjects.
Table 3. Factors affecting the probability that a hypertensive individual will be unaware of having hypertension, China, 2011–2012
Table 4. Factors affecting the probability that a hypertensive individual will not be receiving anti-hypertensive medication, China, 2011–2012
Compared with their female counterparts, hypertensive males were significantly less likely to be aware of their hypertension (Table 3) and to be receiving anti-hypertensive treatment (Table 4). Marital status and household income did not appear to have a significant independent effect on the management of hypertension. However, compared with their literate counterparts, the hypertensive subjects who were illiterate were significantly less likely to be aware of their hypotension (Table 3) and to be receiving anti-hypertensive treatment (Table 4).
Factors associated with the effective control of hypertension are shown in Table 5. Again, the differences seen between urban residents and rural residents could be fully explained by the type of insurance coverage. After adjusting for demographic factors, the RR for the effective control of hypertension among the members of insurance schemes that did not cover outpatient care – compared with the risk among members of other schemes – was 0.869 (95% CI: 0.783–0.965). Further adjustment – to include all of the modifiable risk factors – changed this RR again, to 0.903 (95% CI: 0.817–0.996). The significant association of the type of insurance scheme with hypertension management persisted after adjusting for all other potential differentials. Obesity appears to be the only other investigated factor that had a statistically significant association with the effective control of hypertension (Table 5).
Table 5. Factors affecting the probability that a hypertensive individual will not have the hypertension under effective control, China, 2011–2012
Using data collected in 2011–2012 from the CHARLS national survey, we found that nearly 40% of the inhabitants of China who are aged 45 years or older have some form of hypertensive disorder. Of the interviewees who were found to have hypertension at the time of the interview, more than 40% were unaware of their hypertension and about a half were not receiving any anti-hypertensive medication – irrespective of where they lived or their socioeconomic status. Although high prevalences and poor management of hypertension have been reported in China on several occasions,15–19,34–37 it is disappointing to observe these problems two to three years after substantial reforms to the health system. The management of hypertension in China appears no better than that in other developing countries14,15 and the effective control of hypertension appeared to be as rare in China in 2011–2012 as it was a decade earlier.17,19 Given that hypertension can be prevented and controlled at low cost,8–10 there is no good reason why hypertension in China cannot be managed as well as hypertension in other, more developed countries. In Europe, Japan and North America, for example, more than 80% of hypertensive individuals are aware of their hypertension, more than 80% are receiving anti-hypertensive treatment and more than 60% are controlling their hypertension well.11–13 If the same proportions could be achieved in China, annual mortality among people aged 45 years or older would be reduced by an estimated 860 000 deaths – equivalent to 24 times the annual number of deaths among children younger than 5 years or 130 times the corresponding value for maternal mortality.38,39
Some of our data are encouraging. For example, the proportion of hypertensive individuals who were aware of their hypertension was never found to be more than 9% higher than the corresponding proportion of hypertensive individuals who were receiving anti-hypertensive medication. In other words, almost all individuals in China who know they are hypertensive have access to appropriate treatment. Furthermore, the hypertension in many of the individuals who are receiving anti-hypertensive medication appears to be under effective control. As primary health care becomes increasingly available and affordable in China,24,26 access to effective treatment and control of hypertension continues to improve – and the effective management of hypertension largely becomes a case identification problem. Too many inhabitants of China are unaware that they have hypertension, perhaps because most asymptomatic individuals believe they are healthy and see no benefit in routine health checks. In the CHARLS survey conducted two to three years after a health reform that was designed to establish a heath record and regular health checks for every inhabitant of China, it was very disappointing to see how few of our interviewees had had their blood pressures determined in the previous year. There are several reasons why many cases of hypertension are going undetected in China. The services provided by community health care in the country – which is based on the Soviet Semashko model40 – are often as specialized as those available in general hospitals. However, there are more physicians than nurses available for community health care, and many of the physicians spend most of their working days sitting in their offices, waiting for patients.41 Some of the professionals are unwilling or insufficiently skilled to engage in general practice and preventive care. As a result of these problems in community health care, most of the people who live in China prefer to visit general hospitals for primary care42 and many are, in consequence, never offered the free health checks that should be provided by the community health-care workers. In addition, the monitoring and supervision of community health-care workers are suboptimal. This may explain why about half of the health records that have been created by such workers are considered inadequate.43
Interestingly, we found that the type of health insurance – that is, whether or not the subject’s health insurance covered the costs of outpatient care – was the strongest predictor of the effective management of hypertension in China. Hypertensive individuals with insurance that covered outpatient care were much more likely to be aware of their hypertension – and to be receiving anti-hypertensive medication – than the hypertensive members of other schemes. These associations were independent of setting, demographic factors and socioeconomic status. In large-scale trials, demand-side reimbursements have been found to increase willingness to access outpatient care – particularly the utilization of primary and preventive services.44,45 Given the likely benefits in terms of the early detection of hypertension, the costs of outpatient care need to be included in all health insurance schemes in China. This should not only improve health outcomes but also provide financial risk protection28,29 and improve the management of “catastrophic” chronic conditions in rural areas.27 The current health system in China has been criticized for its fragmentation in providing preventive, primary and tertiary services, which has probably led to the inefficient use of the limited resources and the underuse of community health care.46 However, a more cost-effective, integrated delivery of health services in China is unlikely to be seen before the development of robust and unified financial arrangements.47
Neither marital status nor household income was an independent predictor of the management of hypertension in China but illiterate hypertensive individuals were less likely to be aware of their hypertension than their literate counterparts. Among those who were literate and hypertensive, however, level of education had no apparent impact on awareness. Socioeconomic status had no apparent impact on the effective control of hypertension. Taken together, these observations confirm that the main stumbling block in the effective management of hypertension in China is the identification of hypertensive individuals. Observations on the social determinants of health can help identify modifiable risk factors and guide risk reduction through either system-level multisectoral interventions or individual-level health promotion.48,49 However, behavioural changes to reduce the risk of hypertension are unlikely to be achieved quickly. In addition, in our study, the impact of insurance benefits on the control of hypertension was found to be larger than that of any of the modifiable risk factors that we investigated.
Our data come from the CHARLS survey, which was national and considered to be nationally representative once adjustments had been made for the sampling system. Encouragingly, our estimates of the prevalence of hypertension and of membership in the various health insurance schemes tally with those made in other studies in China.15,18,25,34,37 The close similarity between the weighted and unweighted proportions indicates that the sampling procedure used in the survey was good. It is unclear why hypertension prevalence was relatively high among members of health insurance schemes that covered the costs of outpatient care, although the memberships of the insurance scheme probably differ in certain demographic and lifestyle factors. The classification of four health insurance schemes into just two categories – those that generally covered the costs of outpatient care and those that did not – may have masked scheme-specific associations and within-scheme variations. For example, the Urban Resident Basic Medical Insurance Scheme and the New Cooperative Medical Scheme vary in their benefit packages by region and occasionally cover the costs of outpatient care. However, these schemes only seem to pay for the outpatient care of individuals who have a “severe and catastrophic” noncommunicable disease, such as severe cardiovascular or cerebrovascular complications.25,28,29 Although 20% of the CHARLS interviewees had missing anthropometric measurements – potentially leading to selection bias – these interviewees were fairly evenly distributed in terms of their background characteristics.31 Furthermore, the weighted results – which took account of the missing values – were similar to the crude, unweighted results. As previously, we used Poisson regression to take account of the sampling design and compute robust estimates and RRs.33
Hypertension has become a pressing national problem in China and its control should be on the country’s post-2015 development agenda.50 Following the major health system reform of 2009, China seems to be performing well in delivering effective care to those who are aware of their hypertension. The main challenge that remains is how to identify and reach the many hypertensive individuals who are unaware of their hypertension, especially those who do not present for regular health check-ups or otherwise engage with the health system. Clearly, major changes need to be made to health service delivery in China. The scope of universal health-care coverage should go beyond financial risk protection and include more aspects of primary health care. With concerted efforts in integrating health finances and offering more generous outpatient service coverage, a stronger national health system – that could make huge and rapid improvements in the management of hypertension and other disorders – could be forged in China.
The Program for New Century Excellent Talents in University (NCET-12-0009) funded this study.
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