Bulletin of the World Health Organization

Economic evaluation of hepatitis B vaccination in low-income countries: using cost-effectiveness affordability curves

Sun-Young Kim, Joshua A Salomon, Sue J Goldie

Volume 85, Number 11, November 2007, 833-842

Table 4. Base case results discounted at 3% for a birth cohort of 56 000 infants, assuming 94% coverage of hepatitis B virus (HBV) vaccine

Strategy Total no. cases of new infectionsa Total no. cases of primary liver cancera Total no. cases of premature deathsa Costb Incrementalcostb Effectivenessc Incrementaleffectivenessd Incremental cost–effectiveness ratioe
Societal perspective
No vaccination 41 245 155 161 134 400 295 266
Routine infant vaccination 12 119 21 29 243 600 109 760 291 385 3 881 28
Payer’s perspective
No vaccination 41 245 155 161 0 295 266 0
Routine infant vaccination 12 119 21 29 182 000 182 000 291 385 3 881 47

a Epidemiological outcomes do not vary by perspective.b All costs in 2002 US$.c Effectiveness measured in disability-adjusted life years.d Incremental effectiveness measured in disability-adjusted life years averted.e The incremental cost–effectiveness ratio is the ratio of dollars per disability-adjusted life year averted.